Biofeedback (BF) and its mechanisms of change were examined alongside self-regulation and mind-body approaches in the context of counseling centers. The advance in psychopathology within this context and its intersections with neurophysiological, psychological, and social variables were highlighted. Although BF is commonly provided to students, its effect on self-regulation and mind-body connection remains unclear. There is limited data on the efficacy of treatment modalities in counseling centers, yet with ever-increasing demand for services, it necessitates further study and evaluation for effective planning and resource allocation. Preliminary data from a current study offer important thoughts in this discussion, suggesting that students who receive either individual therapy (treatment as usual) or biofeedback alone tend to report more significant symptom reduction than the combination of these treatments.