Students with learning disabilities (LDs) often need additional supports and structure in inquiry classrooms. The authors describe three ways teachers can enhance the achievement of these students: (1) focusing on big ideas; (2) using graphic organizers; and (3) providing mnemonic strategies. Struggling students with LD will benefit greatly from graphic organizers and the use of mnemonic devices to learn unfamiliar vocabulary. The identification and exploration of the big ideas in connection with a student's prior knowledge can also help create a strong environment of learning for a diverse population of students. Successfully implementing these strategies into science classrooms will prevent students with LD from becoming spectators in a content area filled with hands-on learning. (Contains 3 figures.)