Technology licensing office managers often need to evaluate profitability and commercial potential in their decision making. However, increased consideration of important global public health goals requires forging new collaborative relationships, incorporating creative licensing practices and embracing global public good within the academic and research communities. The authors conducted a survey to identify and document opportunities and barriers in the management of discoveries and inventions arising from global health research outcomes at US and Canadian academic and research institutions. (Contains 5 tables and 4 notes.)