This curriculum guide incorporates the needed components to aid agriculture teachers in the implementation of the Vocational Instructional Management System in biotechnology: applications in agriculture. The guide begins with a list of the competencies/objectives found in the six units; list of references and materials; list of materials and equipment required for activities; list of supply companies; teaching calendar; and competency profile. The curriculum contains six units, each consisting of one to five lessons. Components of each lesson may include the following: an introductory page with lesson title, competency/objective, study questions, and references; transparency masters and activity sheet(s); teaching procedures; motivational techniques; other activities; evaluations; answers to evaluations and activity sheets; references and teaching aids; and materials and equipment. Unit topics include the following: introduction to biotechnology; issues in biotechnology; basic laboratory skills; foundations of genetic engineering; animal technologies; and plant technologies. The student reference contains informational readings for each lesson and a glossary. (YLB)