Today, teachers face more challenges than ever, and biology teachers face a special challenge. As technology continues to expand, biology teachers have a responsibility to keep students informed of technological and scientific advances. Biology teachers must also address ethical issues associated with these advances. In this paper, the authors describe their experiences using "Case It!," a case-based multimedia project for high school and introductory college biology students studying genetic diseases, DNA, gel electrophoresis and related procedures, and ethical issues raised by genetic testing. This software enables teachers to meet several national science standards, such as connecting science to real-life situations and encouraging students to think about the relationships among science, technology and society. The realistic simulation also encourages students to explore careers in molecular biology and genetics, and gives students experience both in building Web pages and Internet conferencing. The effectiveness of this case-based multimedia Internet project has been evaluated over the past five years in both high school and college classrooms. It was found that "Case It!" fit well with science standards and promoted the positive use of technology in schools. Students developed an awareness of ethical issues associated with genetic testing, thus increasing interest by connecting science to real life situations. (Contains 4 figures.)