The education industry has obviously been influenced by the Internet revolution. Teaching and learning methods have changed significantly since the coming of the Web and it is very likely they will keep evolving many years to come thanks to it. A good example of this changing reality is the spectacular development of e-Learning. In a more particular way, the Web 2.0 has offered to the teaching industry a set of tools and practices that are modifying the learning systems and knowledge transmission methods. Teachers and students can use these tools in a variety of ways aimed to the general purpose of promoting collaborative work. The editor would like to thank the authors, who have committed so much effort to the publication of this work. She is sure that this volume will certainly be of great help for students, teachers and researchers. This was, at least, the main aim of the authors. This book contains the following chapters: (1) Enhancing On-line Blended Learning Systems Using a New Human-Computer Interaction Educational Methodology (Ismael Pascual-Nieto, Diana Perez-Marin, Mick O'Donnell and Pilar Rodriguez); (2) A Conceptual and Technological Framework for Building Collaborative Learning Environments (Lonchamp Jacques); (3) Concerto II: A Collaborative Learning Support System Based on Question Posing (Atsuo Hazeyama and Yuuki Hirai); (4) A Collaborative Medical Case Authoring Environment Based on the UMLS (Siriwan Suebnukarn); (5) The Interaction Analysis with the ADULT environment (A pilot study) (Alexandra Gasparinatou, Grammatiki Tsaganou and Maria Grigoriadou); (6) Mobile Learning: Two Experiments on Teaching and Learning with Mobile Phones (Adelina Moura and Ana Amelia Carvalho); (7) Designing Collaborative Authoring Tools for Mobile Learning (Alexandre Antonino Goncalves Martinazzo and Roseli de Deus Lopes); (8) Development of InfoStation-based and Contextaware mLearning System Architectures (Ivan Ganchev, Stanimir Stojanov, Mairtin Odroma and Damien Meere); (9) An Interactive Simulation Game to Enhance Learners' Experience on Ubiquitous Computing Devices (Vincent Tam, Zexian Liao, C.H. Leung, Lawrence Yeung and Alvin C.M. Kwan); (10) Augmented Reality and Tangible Interfaces for Learning (M. Carmen Juan Lizandra); (11) New Ways for Learning and Knowledge Transfer Using Social Semantic Technologies (Gisela Granitzer, Armin Ulbrich, Klaus Tochtermann and Reinhard Willfort); (12) The Use of XML to Express a Historical Knowledge Base (Katsuko T. Nakahira, Masashi Matsui, Kazutoshi Abiko and Yoshiki Mikami); (13) Free Text Response Assessment System Based on a Text Comprehension Model (Panagiotis Blitsas and Maria Grigoriadou); (14) A Software System for Inference-Based Context-Aware Vocabulary Learning (Yukiko Sasaki Alam); (15) A Web-based Multimedia Annotation System for Language Learning (Kuo-Yu Liu and Herng-Yow Chen); (16) Effects of Media Richness on User Acceptance of Web 2.0 Technologies in Higher Education (Nauman Saeed and Suku Sinnappan); (17) Supporting Learning in Online Communities with Social Software: an Overview of Community Driven Technologies (Stefanos Ziovas, Maria Grigoriadou and Maria Samarakou); (18) Improving the Analysis of Students' Participation & Collaboration in Moodle Forums (Raquel Hijon-Neira and Angel Velazquez-Iturbide); (19) A Framework for Dynamic Sequential Behavioral Pattern Detecting and Automatic Feedback/Guidance Designing for Online Discussion Learning Environments (Huei-Tse Hou); (20) Towards the Integration of Adaptive Educational Systems with SCORM Standard and Authoring Toolkits (Ioannis Kazanidis and Maya Satratzemi); (21) Impact of Standardisation and Open Source Software in e-Learning (Kiyoshi Nakabayashi); (22) Application of E-Learning Standardization Technology (Li Zheng, Lei Xu and Yushan Li); (23) Managing Relevant Learning Objects' Assessments: the Right Place at the Right Time (Olivier Catteau, Philippe Vidal and Julien Broisin); (24) Learning Paradigms through Fundraising Systems: the RoboBeggar and the InfoKiosk Cases (Gaetano La Russa, Erkki Sutinen and Johannes C. Cronje); (25) Learning in Bioelectronics (Cristian Ravariu); (26) Guidelines for Designing and Teaching an Effective Object-Oriented Design and Programming Course (Stelios Xinogalos); and (27) Educational Effect of Externalization of Know-how Information for Care Planning Processes (Kaoru Eto, Tatsunori Matsui and Yasuo Kabasawa).