Obesity and being overweight, as determined by body mass index (BMI), each continues to be of concern for many Native American/American Indians (NA/AI). According to the "Diagnostic and Statistical Manual of Mental Disorders," binge eating is excessive eating or consuming large quantities of food over a short period of time and has been associated with psychological distress. Among a sample of NA/AI women, this study explored the linear relationship of historical loss, acculturation, racism, and emotional distress to binge-eating behavior and level of obesity as determined by BMI. Emotional distress, experiences of racism, and feelings about historical loss were significantly related to binge-eating behaviors, with emotional distress being the most significant predictor.