The Universal eLearner is an online integrated learning module, under development, that incorporates accessible technology, universal design for learning, and best practices for online education. The American Foundation for the Blind and Bridge Multimedia have just completed a three-year grant through the National Institute on Disability and Rehabilitation Research, U.S. Department of Education, to develop and test the latest version of the Universal eLearner. The Universal eLearner, although not a finished product, has been developed and field-tested with students with disabilities (including those with visual impairments, hearing impairments, orthopedic impairments, and learning disabilities), as well as students who are English language learners and typically developing students. The evaluations conducted under the grant focused on the accessibility and usability of the Universal eLearner to provide feedback to the development team to improve the product further. This report presents some of the outcomes from the grant-funded project to help professionals understand the needs of students with disabilities in relation to integrated learning modules and to offer suggestions for anyone who is developing universally accessible online educational programming.