Multiracial Americans represent a rapidly growing population (Shih & Sanchez, 2009); however, very little is known about the types of challenges and resilience experienced by these individuals. To date, few psychological measures have been created specifically to investigate the experiences of multiracial people. This article describes 2 studies focused on the development and psychometric properties of the Multiracial Challenges and Resilience Scale (MCRS). The MCRS was developed using a nationwide Internet sample of urban, multiracial adults. Exploratory factor analyses revealed 4 Challenge factors (Others' Surprise and Disbelief Regarding Racial Heritage, Lack of Family Acceptance, Multiracial Discrimination, and Challenges With Racial Identity) and 2 Resilience factors (Appreciation of Human Differences and Multiracial Pride). A confirmatory factor analysis with data from a second sample provided support for the stability of this factor structure. The reliability and validity of the measure, implications of these findings, and suggestions for future research are discussed. (Contains 3 tables and 1 footnote.)