In this longitudinal study, we investigated the mechanisms by which Chinese American parents' experiences of discrimination influenced their adolescents' ethnicity-related stressors (i.e., cultural misfit, discrimination, attitudes toward education). We focused on whether parents' ethnic-racial socialization practices and perpetual foreigner stress moderated or mediated this relationship. Participants were 444 Chinese American families. Results indicated no evidence of moderation, but we observed support for mediation. Parental experiences of discrimination were associated with more ethnic-racial socialization practices and greater parental perpetual foreigner stress. More ethnic-racial socialization was related to greater cultural misfit in adolescents, whereas more perpetual foreigner stress was related to adolescents' poorer attitudes toward education and more reported discrimination. Relationships between mediators and outcomes were stronger for fathers than for mothers.