This publication encourages student involvement in biological research through student research with the cooperation of teachers and scientists. The contents of the book are divided into two sections. The first section introduces students to research investigations and includes: (1) "How the Investigations Are Set Up and the Rationale Behind Their Designs"; (2) "Background on the Writing Partnerships between the High School Teachers and Scientists"; (3) "Some Practical Points about Experimental Design and Open-Ended Investigations"; (4) "Safety Issues Involved in Student Research"; (5) "General Guidelines for Supervising Student Research"; (6) "Where to Find Mentors and the Role They Play in Student Research"; (7) "Where to Find Student Research Opportunities"; (8) "Modifying These Investigations for Students Who Are Exceptional"; and (9) "How the Student Research Investigations Address Assessment and Standards". The second section focuses on student research core laboratory investigations with variations and includes: (1) "A Study of Allelopathy in Plants"; (2) "Biosphere 3--It's a Small World After All"; (3) "Tolerance Testing with a Hairless "Guinea Pig"; (4) "A Community Underfoot: Density and Diversity of Invertebrates in Soil or Ground Cover"; (5) "Isolation of Nutritional Mutants of E.Coli"; (6) "Which Way to Grow: Exploring Tropic Responses of Plants"; (7) "The Impact of Mollusks on Water Quality"; (8) "Plant Tissue Culture: Embryo Isolation and Tissue Culture Initiation"; (9) "A Study of Snail Behavior"; (10) "Stressed Out Plants"; and (11) "Nature's Early Warning Systems". Appendices include: (1) "Writing Format for Student Research"; (2) "Resources on the NABT Web Site"; (3) "Standard Microbiological Practices and Aseptic Techniques"; (4) "Tips for Conducting Multiple Student Research Activities"; (5) "Competitions for Student Research Activities"; and (6) "Student Research Evaluation Form". (YDS)