Previous research on pubertal timing has either evaluated contextual predictors of early puberty or negative adjustment outcomes associated with off-time development, especially early maturation. In this study, we integrated these 2 lines of research by evaluating the moderating influence of early childhood household risk on associations between early puberty and 8th-grade substance use in a longitudinal sample of 1,070 participants. We determined trajectories of early childhood household risk using group-based trajectory analysis. Rates of early maturation were higher but not significantly so in groups with high household risk. Early timing was associated with higher rates of substance initiation only among individuals with a history of high household risk. (Contains 1 figure, 3 tables and 5 footnotes.)