This publication reports the results of a review of scientific research on office job hazards, survey responses from more than 1,200 office workers in Cleveland and Boston, and in-depth interviews with more than 100 office workers. The report covers the following areas of health hazards for office workers: (1) job stress--physical and psychological effects; (2) health problems associated with video-display terminals (VDTs), the major components of office automation; (3) office air quality and ventilation; (4) office environment: noise, improper lighting, and workplace and machine design; and (5) safety hazards (accidents, injuries, and fire hazards). The sources and health effects of each hazard are documented, and recommendations are made for research and action needed to correct the problem. Because the dangers in the office have only recently been recognized, protective standards have not yet been developed. The report urges a variety of steps toward a safe and healthful workplace for office workers--increased public attention to office hazards, manufacturer and employer action to reduce hazards, employee action to identify and address common problems, and government action to set and enforce standards for safe office working conditions. (KC)