Students in undergraduate organic chemistry courses are frequently overwhelmed by the volume and complexity of information they are expected to learn. To aid in students' learning of organic functional groups, a novel card game "ChemKarta" is reported that can serve as a useful alternative to flashcards. This pedagogy is a simple matching game, in which students identify functional groups on molecules. ChemKarta has a large card set to immerse students in course material and to allow teachers to mine the game for class and exam questions. It is easily customized by the addition or removal of cards to adjust content to fit an individual course. Students found the game easy to learn and responded favorably to its use as an educational tool.