This study was undertaken to design a biology training program for secondary school teachers in the Mekong Delta region of Vietnam. The methods reported in this study included an analysis of the current biology training programs with reference to a set of biology objectives developed in the 1970 curriculum revision. Second, modern developments in biology education programs in the United States were reviewed. Third, an analysis of the socio-economic aspects of the Mekong Delta region was made to determine needs and demands so that the selected curriculum would have a direct application to the immediate environment. Public health, agriculture, and fisheries were chosen as areas of emphasis for the major course content and experiences. The criteria for planning the program involved: (1) the program should be a four-year sequence; (2) biology teachers should have a broad minimum competency in related sciences; and (3) teachers should have sufficient strong training in their major area. The program formulated included three components: Biology, 40-45 semester credits (sc); Related Sciences, 36-37 sc; and Other Program Components, 58-64 sc. The program consists of two units: Introductory Biology and Advanced Biology. A devised laboratory approach is described. Recommendations for implementing the proposed program are presented. (Author/EB)