Although disordered eating behaviors are relatively common among college women, many questions about their etiology remain. In the present study, structural equation modeling was used to investigate potential mediating associations among variables previously found to be associated with the continuum of disordered eating behaviors in a large sample of college women. Results indicated that family conflict, family cohesion, and childhood physical and emotional abuse and neglect were not directly associated with disordered eating. Rather, their association with disordered eating was mediated by alexithymia and depression. These results were cross-validated in a second sample of college women. These data highlight the complexity of disordered eating and provide future directions for the prevention and treatment of the continuum of disordered eating behaviors.