Phonological process analysis was carried out using a 40-word imitation task with 30 11;6-14;6 year old Kannada-speaking persons with Down syndrome in comparison with 15 non-verbal mental age matched typically developing children. Percentages of occurrence were significantly higher for the Down syndrome group with certain exceptions. Some phonological processes were observed only in the Down syndrome group. Kannada is a non-Indo European language spoken in the southern Indian state of Karnataka that has not had much research attention, especially with respect to persons with communication disorders. This paper highlights the phonological processes observed in school-aged persons with Down syndrome, some of which are similar to those observed in English and Dutch (cluster reduction, stopping, gliding, consonant harmony) and others that differ owing to differences in Kannada's phonology (e.g. retroflex fronting, degemination). The study gives a cross-linguistic perspective to the study of phonological processes in Down syndrome. (Contains 4 tables.)