The study investigated the efficacy of a dialectical behavior therapy (DBT) program with a general college counseling center population, not limited to students diagnosed with borderline personality disorder. A review of records of 64 students found that obsessive-compulsive symptoms, interpersonal sensitivity, depression, anxiety, paranoia, somatization, psychoticism, and phobic anxiety decreased, as did overall distress. All four target areas of DBT, namely confusion about self, impulsivity, emotional dysregulation, and interpersonal chaos, also significantly decreased. Limitations and implications for college counseling centers are discussed.