This article features Ohio teacher Carol Fleck's use of videoconferencing in teaching Contemporary BioScience and Genetics. Fleck, who says her initial vision for the class was "science without classroom walls," covers such topics as emerging diseases, bioterrorism, and forensic science. Collaboration between schools is a key part of the course experience. Students pair up with students in Kirtland, communicating by videoconference, telephone, fax, online chats, and e-mail to create a product that can be shared with the wider community.