The experimental analysis of behavior has identified several molar functional relations that are highly relevant to clinical behavior analysis. These include matching, discounting, momentum, and variability. Matching provides a broader analysis of how multiple sources of reinforcement influence how individuals choose to allocate their time and offers an empirical rationale for reducing problem behavior by increasing adaptive behavior. Discounting highlights the functional relations that affect self-control. Momentum specifies the variables responsible for persistence in challenging situations. Variability characterizes a functional dimension of behavior that is essential for learning and problem solving. These concepts have important implications for clinical practice and research. A selective review of these concepts is presented, and their implications for assessment and treatment are discussed with two goals: to inform basic scientists about the relevance of their work and to invite clinical behavior analysts to broaden the conceptual basis for their work. (Contains 2 figures.)