Design-based research is a burgeoning research paradigm holding the promise of introducing more socially responsible studies to transform education. However, there is a lack of methodological standards and established research processes to inform this type of study. Although there are general principles and procedures on design-based research, little guidance is available to researchers with regard to how to conduct design-based research at the individual iteration level when creating technology-based innovative learning environments. In this article, we describe a case study of design-based research in a single iteration, illustrate a research and development process evolved from this study, and present several guidelines on how to conduct design-based research. (Contains 2 figures.)