Interlibrary Loan borrowing rates in academic libraries are influenced by an array of factors. This article explores the relationship between interlibrary loan borrowing activity and research activity at 42 Canadian academic institutions. A significant positive correlation was found between interlibrary loan borrowing activity and measures of research activity. The degree of correlation observed depended on the category of institution, with undergraduate and comprehensive universities showing the largest correlations. This is the first study to quantify the relationship between interlibrary loan and research activity, and the findings suggest that interlibrary loan plays a role in supporting academic research at Canadian universities.