Although researchers argue that single parents perceive more work-family conflict than married parents, little research has examined nuances in such differences. Using data from the 2002 National Study of Changing Workforce (N = 1,430), this study examines differences in home-to-job conflict by marital status and gender among employed parents. Findings indicate that single mothers feel more home-to-job conflict than single fathers, married mothers, and married fathers. Some predictors of home-to-job conflict vary by marital status and gender. Job pressure is related to home-to-job conflict more for single parents than for married parents. Age of children is related to conflict for single fathers only. Whereas an unsupportive workplace culture is related to conflict especially for married fathers, the lack of spouses' share of domestic responsibilities is related to conflict especially for married mothers. These findings indicate that marital status and gender create distinct contexts that shape employed parents' perceived home-to-job conflict. (Contains 2 figures and 3 tables.)