Higher learning based instruction may be primarily concerned in most cases with the content of their academic lessons, and not very much with their instructional delivery. However, the effective application of learning theories and technology in higher education has an impact on student performance. With the rapid progress in the computer and multimedia technologies, it has become feasible to integrate multimedia technologies into the teaching and learning process. What has been the conventional teacher-centered teaching approach is now seeing a shift into one which emphasises on student-centered learning approach. There is a body of evidence that supports the benefit of using technology, such as multimedia elements in the form of 2-Dimension (2-D) and 3-Dimension (3-D) animation to assist in learning. The domain knowledge applied in this study was on a Computer Science subject, particularly on Operating Systems, for the topic on "Memory Management". Memory management is one of the topics taught in the course on Operating Systems in Computer Science and Information Technology programmes. This paper discusses the applicability of some learning theories, Mayer's Cognitive theory of Multimedia learning, and the use of animation in computer science education. Finally screen designs of the multimedia learning prototypes are displayed in 2-D and 3-D animation. (Contains 14 figures.)