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ERIC Number: EJ933552
Record Type: Journal
Publication Date: 2011-Aug
Pages: 19
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-1076-9986
EISSN: N/A
The Design of Cluster Randomized Crossover Trials
Rietbergen, Charlotte; Moerbeek, Mirjam
Journal of Educational and Behavioral Statistics, v36 n4 p472-490 Aug 2011
The inefficiency induced by between-cluster variation in cluster randomized (CR) trials can be reduced by implementing a crossover (CO) design. In a simple CO trial, each subject receives each treatment in random order. A powerful characteristic of this design is that each subject serves as its own control. In a CR CO trial, clusters of subjects are randomly allocated to a sequence of interventions. Under this design, each subject is either included in only one of the treatment periods (CO at cluster level) or in both periods (CO at subject level). In this study, the efficiency of both CR CO trials relative to the CR trial without CO is demonstrated. Furthermore, the optimal allocation of clusters and subjects given a fixed budget or desired power level is discussed. (Contains 4 tables and 3 figures.)
SAGE Publications. 2455 Teller Road, Thousand Oaks, CA 91320. Tel: 800-818-7243; Tel: 805-499-9774; Fax: 800-583-2665; e-mail: journals@sagepub.com; Web site: http://sagepub.com
Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A