Objective: The purpose of the current study was to examine medication vacations among children with ADHD according to parent-child dyads (e.g., mother-son, father-daughter, mother-daughter, and father-son). Method: In a survey study of 259 parents of children with ADHD, the use of medication vacations according to parent-child sex dyads was examined. Results: Results of the current study suggest that fathers seem to report endorsing medication vacations more with their sons with ADHD as opposed to their daughters with ADHD. There did not seem to be any significant differences among mothers. Conclusion: Results of the current study conclude with directions for future research and practice. (Contains 1 table.)