It is important that first responders remain aware of the possible hazards resulting from chemical accidents or the intentional use of chemicals in destructive devices. Chemical components can be utilized in the manufacturing of improvised explosive devices (IEDs), can enhance the effect of a more conventional device, or can pose hazards based on their own properties. Chemical components may be popular with young offenders or anyone who can gain access to such materials, some of which can be purchased "off-the-shelf." Besides purchasing them, one place to obtain chemical ingredients for unsophisticated yet functional IEDs can be academic institutions' science and chemistry laboratories. Certainly not all, but some "classrooms and laboratories may contain a variety of dangerous chemicals that are outdated, inappropriate, toxic, reactive, and explosive." Furthermore, academic institutions themselves may be the location of bomb or fire related incidents and these chemical components can create additional hazards at the scene. Being able to identify chemical packaging and labels can offer some protection by lending clues as to the dangerous properties of the product. Training exercises, a review of basic hazardous materials awareness principles, and good rapport between campus and local officials can help first responders gain a better understanding of the unique hazards associated with a response in proximity to a chemistry lab (whether school, university, or research facility). In addition, the training exercise can serve as a good Haz-Mat refresher when it incorporates a multi-agency response, the implementation of Incident Command System (ICS) principles, the use of Emergency Response Guides and Material Safety Data Sheets, along with the proper selection and use of Personal Protective Equipment. (Contains 8 notes.)