In this paper, we examined dimensions of child health-related quality of life in Greece in relation to parental assessments of neighbourhood social capital and social support networks. For the analysis, two main measures were used: (1) child self-reported health-related quality of life in ten dimensions, as measured by the KIDSCREEN questionnaire; (2) subjective measures of parental neighbourhood social capital and social support. Parental assessments of neighbourhood social capital and social support were both independently and positively associated with child self-reported health-related quality of life. However, they were not associated with the same dimensions of child well being, nor were they associated with all dimensions of child well being. These results suggest that greater attention in future research needs to be paid to the differential associations between the various dimensions of social capital and child health-related quality of life, with clear focus implications for social and health policies.