This proceedings of the 2000 Topics on Distance Learning conference contains summaries of the following presentations: "The ABC's of Distance Learning via Full Motion Video" (Liz Owens); "Assessing the Cost of Technology in Instruction Using an Economic Model" (Joseph Lovrinic); "Collaboration Lessons Learned from the Learning Cooperative" (Liz Owens); "Computer Based Alternative Testing Using Test Pilot" (Janice Tazbir and Maureen Marthaler); "Current Controversies in Organizing Distance Education: Intellectual Property, Staffing, and Business Relations" (Jo Ann Oravec); "Distance Learning--A Collaborative Community" (Marie Crabb); "Improving Student Performance in Distance Learning Courses" (Judy Serwatka); "Making Websites Universally Accessible: Ensuring Web Access for Students with Disabilities" (Dean Brusrighan); "The New Frontier of Web-Based Business Education Courseware" (Tom Opper); "The 'Pluses' of Collaborative and Interactivity Learning via Two-Way Interactive Television in a Multicultural Setting: A Case Study, City Colleges of Chicago" (Audrey Turner); "Principles and Guidelines for the Instructional Development Process of the Web-Based Instruction" (Li-An Ho); "Streaming Lectures over the Internet" (David McLees and Michael O'Toole); "Teachers in Hardhats: A Collaborative Solution to a National Shortage" (Jane Swiss and Karla Alexander); "Teaching Science Fiction Online: Experiences with a Web-Only Class" (William Dynes); "Technical Support in Distance Education" (Anastasia Treckles); "Training at the Speed of Technology" (Candy Matheson);"Using a Wrench To Pound in a Screw: The Misapplication of Communication Technologies in Education" (Eric Wignall); and "Web-Based Delivery of a Graduate Nursing Course (Guess What? It Was Fun and Successful!)" (Gail Wegner). (MES)