Latino men who have sex with men are a group at high risk for HIV infection. Much of the research addressing attitudes and behaviors related to HIV among Latinos in the United States has overlooked differences based on nationality. Brazilian immigrants, in particular, are an understudied subgroup of Latinos. This study compared HIV-positive Brazilian gay men (n = 75) with their Spanish-speaking counterparts from South America (n = 103) and Puerto Rico (n = 61) on a variety of HIV-related factors. Results failed to reveal any significant group differences in disclosure of serostatus or in behaviors relevant to sexual risk. Some differences in demographic characteristics, reasons for immigration, and acculturation, however, did emerge among the three groups. Implications for aggregation of Latino subgroups in HIV-related programs are discussed.