Laboratory demonstration, as well as biochemistry lecture, has been used to complement explanation of biochemical processes. The laboratory demonstration is very useful in teaching biochemistry to students who lack background in biology. The experimental model of fibrinolysis described here presents a complex biological reaction in simplified manner, emphasizing specific terms related to enzymes, and triggers student interest in biochemistry. The following are appended: (1) Equipment and Consumables; (2) Reagents; (3) Safety Precautions; and (4) Calculation of Fibrinolytic Activity from Students' Sample Data. (Contains 2 figures and 3 tables.)