One of the fastest-growing categories of disability in the college student population is psychiatric disabilities: bipolar disorder, anxiety disorders, and borderline personality disorders, among other. Appropriate treatment and support can provide students with psychiatric disabilities the opportunity to develop their talents and realize their potential, culminating in their successful navigation of college. Yet these disabilities are the least understood and least academically supported on campus. The fundamental challenge for student affairs professionals is that their educational and experiential preparation has not accounted for the complexity of working with students with psychiatric disabilities. Characteristically, disability support providers are the experts; however, the issues and concerns extend far beyond the work of disability support providers and must include generalist student affairs practitioners, administrators, and faculty. This chapter examines the population, describes the prevalence of this group on college campuses, offers a definition of psychiatric disability, and addresses the issues, concerns, and experiences of these students, faculty, and student affairs professionals. This chapter also addresses the value of inclusion and integration of students with psychiatric disabilities on college campuses, offers strategies for inclusion and integration in and outside the classroom, and provides a comprehensive model of support.