The objective of this study is to assess the effects of the unique 1-year health-wellness program of exercise and health education for obese youth on body mass index (BMI) and blood pressure. The CEMHaVi program included 74 obese children. Participants, 19 girls and 18 boys, and controls, 17 girls and 20 boys, were assigned to treatment. The treatment participants were compared with a group who chose not to participate. Treatment consisted of a unique program of physical activity that emphasized playing games. Activity sessions were offered once per week, 2 h each session, for 12 months. Physical activity was complemented with health education. Controls received only the normal care of a physician in pediatrics. Physical and physiological measures were assessed before and after intervention. Findings of the study showed a significant difference in BMI between treatment and control participants (P less than 0.05). BMI decreased in the treatment group and increased in controls. There were no significant differences in blood pressure. In conclusion, results of the study suggest that a unique program of exercise and health education had beneficial effects on BMI in obese youth after 1 year. The feasibility of a beneficial lifestyle intervention program is encouraging.