Based on experiences gained during the Girls into Science and Technology (GIST) project, this report reviews practical suggestions for teaching science to mixed classes in ways that encourage girls to become more involved in the sciences. Chapter 1 provides data about sex differences in examination entries and women's representation in professional and managerial occupations. Results of an attitude survey of 11-year-olds in Great Britain are discussed in Chapter 2 and the causes of girls' underachievement in the physical sciences are explored. The next three chapters focus on needed changes in the laboratory/classroom, curriculum, and in written materials. Chapter 6 suggests ways of counteracting the concept that science and technology are exclusively male preserves. A list of references and suggestions for further reading are also included. Appendices consist of: (1) a list and descriptions of the career areas of women visitors to science classes; (2) examples of the GIST project workcards; (3) two worksheets on women scientists; (4) brief biographies of women scientists; and (5) model illustrations of girls performing standard lab operations. (ML)