This guide is designed to assist secondary school teachers in developing sequential drug education activities for infusion into the general curriculum, particularly in the communicative arts areas. The scope of the materials encompasses health habits, drug use and abuse, drug laws, and the pharmacology of drugs in specific sections by subject matter. Each section, delineated by grade level, is organized according to objective, content, and learning activities. The narrative provides accurate, current information on the history of drug use/abuse, pharmacology of drugs, social/psychological implications of drug use and drug treatment/rehabilitation. Sections on affective education to assist students in choosing alternatives to drugs, a list of state-wide drug education resource centers and materials, and reviews of drug education audiovisual aids are also provided. (Author/HLM)