The purpose of this study was to determine students' perceptions of learning gains when using the one-minute paper. Thirty-one students from the Physical Therapy (PT) and Nurse Anesthesia (NA) programs participated in this study. Students completed the one-minute paper in three classes. An email to students clarified the "muddy" points and included a link to the online survey. The Mann-Whitney Test was used to assess the significance of mean ranks of the survey question responses between the NA students and the PT students and to assess significance of age on the survey responses. Students reported less learning gains from the one-minute paper as compared to lectures and class discussions. However, students indicated that the one-minute paper enhanced their connection of key ideas with prior knowledge and application of concepts. Younger students reported less learning gains from group participation. Students appeared to value the use of the one-minute paper to make connections with other course material and for application of knowledge. Use of the one-minute paper to enhance learning is supported.