The purposes of this study were to: 1) Examine the effect of RMS learning model towards critical thinking skills. 2) Examine the effect of different academic abilities against critical thinking skills. 3) Examine the effect of the interaction between RMS learning model and different academic abilities against critical thinking skills. The research method used was quasi experimental with 2x2 factorial pretest posttest nonequivalent group design.The critical thinking skills instrument used was essay test with the high level of reliability is 0.712. The data analysis used descriptive analysis and ANACOVA statistical analysis. The results showed that RMS learning model effectively improved students' critical thinking skills and was able to align students critical thinking skills in different academic abilities. The impact of RMS learning model is higher 55,6% than conventional model on critical thinking skills. The basic concepts of science and biology lecturer were recommended to apply RMS learning model to apply them in high schools, middle schools, and elementary schools.