This study explored the impact of a 4-week skills group intervention based on the principles of Dialectical Behavior Therapy (DBT) with a sample of adolescents attending a Disciplinary Alternative Education Program. This article provides a session-by-session overview of activities adapted from DBT-specified training modules of mindfulness, emotional regulation, interpersonal effectiveness, and distress tolerance. The results of a pre/posttest comparison revealed reductions in student- and parent-reported indicators of behavioral distress when compared to a control sample of students not receiving the intervention. Implications and continuing challenges of conducting efficacy studies of clinical interventions in schools are discussed.