This paper examines factors that influence the post-adoption satisfaction of educators with e-learning systems. Based on the expectation-confirmation framework, we propose a research model that demonstrates how post-adoption beliefs affect post-adoption satisfaction. The model was tested at a university by educators (n = 175) who use an e-learning platform to conduct their teaching. The results suggest that post-adoption satisfaction is driven by confirmation, perceived system quality, perceived usefulness, perceived work compatibility and perceived support. These core determinants of satisfaction explained around 83% of the total variance of satisfaction in this study. (Contains 3 figures and 6 tables.)