Prior research has inconsistently documented the gendered nature of negative spillover between the domains of home and work. Little is known about predictors of negative spillover for employed mothers and fathers. Using the 1997 wave of the National Study of the Changing Workforce, this study's purpose was twofold: to determine if a difference exists in negative spillover for working mothers and fathers and to identify shared and unique predictors of spillover for both groups. Findings reveal that more working mothers than fathers in the sample experienced negative family-to-work spillover. Time spent performing household chores and caring for children by respondent and spouse did not predict negative spillover for mothers, although caring for a sick child was a significant predictor for fathers. Marital satisfaction was not a significant predictor of spillover, whereas family life satisfaction was one of the strongest predictors for both mothers and fathers.