This study used records from a state-operated comprehensive rehabilitation center to investigate possible predictive factors related to completing comprehensive rehabilitation center programs and successful vocational rehabilitation (VR) case closure. An analysis of demographic data of randomly selected comprehensive rehabilitation center participants served between fiscal year (FY) 1998-1999 and FY 2003-2004 indicated that participants were by and large younger than participants in the general VR program, with many center participants having psychological or cognitive primary disabilities. A binary logistic regression identified completing a comprehensive rehabilitation center program as a predictor of successful VR case closure, whereas receiving psychological services, being from a rural area, and receiving public assistance were negative predictors of successful VR case closure. (Contains 3 tables.)