This study provided a test of the multiple criteria concept used for lexical decision, as implemented in J. Grainger and A. M. Jacobs's (1996) multiple read-out model. This account predicts more inhibition (or less facilitation) from a masked neighbor when accuracy is stressed more but more facilitation (or less inhibition) when the speed of responding is emphasized more. The authors tested these predictions by stressing accuracy (Experiment 1) and response speed (Experiment 2). The results of Experiment 1 showed a stronger neighbor-inhibition effect in the stress-on-accuracy condition than in the control condition. The results of Experiment 2 showed facilitation because of the neighbor prime in the stress-on-speed condition relative to the control condition. These results corroborate the multiple criteria account.