This study evaluated whether two persons with developmental disabilities would be able to improve their pointing performance through a Dual Cursor Automatic Pointing Assistive Program (DCAPAP) with a newly developed mouse driver (i.e., a new mouse driver replaces standard mouse driver, and is able to intercept/detect mouse movement action). First, baseline sessions started with both participants. Then the first participant had his intervention session. When his performance was consolidated, new baseline and intervention occurred with the second participant. Finally, both participants were exposed to maintenance phase, in which their pointing performance improved significantly. Data showed that both participants improved their pointing efficiency through the use of DCAPAP and retained their successful results through maintenance phase. Implications of the findings are discussed. (Contains 5 figures.)