In this article the author's review of the literature uncovers six potentially negative effects of technology in the classroom. These include: 1) Limiting pedagogy in teaching for cultural competence; 2) Reinforcing the Digital Divide; 3) Constraining the potential for holistic, humanistic education; 4) Privileging one style of communication while limiting broader approaches; 5) Transforming teaching into a form of sensory deprivation; and 6) Diminishing standards of academic excellence in the classroom. These negative effects may pose serious consequences for teaching and learning. The author argues that uncritically adopting technology may run counter to some of our most cherished values: multicultural competence, equity, a humanistic approach to teaching, versatile and flexible modes of communications, and academic excellence. The article concludes with suggested guidelines and a summary of best practices for assuring that when classroom technology is used, it can be used wisely, selectively and with an understanding of its implications to teaching for excellence and inclusion. (Contains 1 footnote.)