The purpose of this study was to evaluate the effects of computer-based video instruction (CBVI) on teaching grocery purchasing skills to students with moderate intellectual disability (ID). Four high school students with mild to moderate ID participated in the study. A multiple-probe design across students was used to examine the effects. Results indicated that using CBVI independently was an effective method for facilitating the acquisition and generalization of grocery purchasing skills by students with ID. The four students in the study acquired and generalized these skills to actual grocery stores. Limitations and suggestions for future research are discussed.