The purpose of this study was to examine sensory quadrants in autism based on Dunn's Theory of Sensory Processing. The data for this study was collected as part of a cross-sectional study that examined sensory processing (using the Sensory Profile) in 103 persons with autism, 3-43 years of age, compared to 103 age- and gender-matched community controls. Sensory quadrants (Low Registration, Sensation Seeking, Sensation Sensitivity, and Sensation Avoidance) on the Sensory Profile are different in persons with autism as compared to community controls, with persons with autism engaging in the behaviors more frequently than the controls. This study provides further evidence of sensory differences in autism.