This article focuses on science, technology, engineering, and mathematics (STEM) education in secondary inclusive classrooms. Co-teaching is increasingly used in inclusive practice by administrators to provide effective instruction in inclusive classrooms. The practical and successful instructional strategies in the article focus on one co-teaching structure: station teaching. Although co-teaching has six different models, station teaching can provide a meaningful way for general educators and special educators to work collaboratively in the STEM inclusive classroom. This article will demonstrate the technology and communication enhancement that are necessary in STEM careers. (Contains 2 tables, 1 figure and 3 online resources.)