Many schools are currently faced with the difficult task of including increasing numbers of students with disabilities and improving academic outcomes for these and other students who struggle to learn academic content. Recent research has shown that the principal is the key to ensuring that a school meets both of these goals and is both inclusive and effective. A case study was conducted of a highly effective, inclusive school that examined the role of the principal in ensuring the success of the school. The principal ensured that this school was successful by collaborating with teachers to set the direction for the school; redesigning the organization; improving working conditions; providing high-quality instruction in all settings; and using data to drive all decision making.