We explored the role of enabling school structures, trust in the principal, collegial trust, and collective efficacy in 15 pre-Kindergarten to 12th grade international, private schools in South and Central America. While the majority of these schools shared an "American" curriculum that was taught predominantly in English, we found that local culture and school norms affected the development of professional learning communities (PLCs) in each school and country accordingly. As enabling school structures, trust in the principal, collegial trust, and collective efficacy were more established, the PLC was more likely to be developed based upon teacher perceptions in this quantitative study.