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ERIC Number: EJ988911
Record Type: Journal
Publication Date: 2012-Apr-10
Pages: 3
Abstractor: As Provided
ISBN: N/A
ISSN: ISSN-0021-9584
EISSN: N/A
Using Group-Inquiry to Study Differing Reaction Conditions in the E2 Elimination of Cyclohexyl Halides
Long, Robert D.
Journal of Chemical Education, v89 n5 p672-674 Apr 2012
In this experiment, students individually conduct one of several variations of an E2 dehydrohalogenation reaction on a cyclohexyl halide substrate for 30 min, which is sufficient only for a partial reaction to occur. The variations examine reaction conditions including different leaving groups, decreased reaction temperature, or reduced base concentration. Analysis of the quenched reaction products by GC or NMR allows students to compute the percent completion of their individual reaction. In a subsequent lab, the student results are compiled and averaged, and statistics are generated. The students perform a collaborative group analysis to draw conclusions as to how the different factors affected the rate of reaction based on percent completion and the impact of any errors observed. The statistical compilation of data from repeated trials for the group analysis demonstrates to students an approach to research that is analogous to real-world research technique. (Contains 1 scheme and 1 table.)
Division of Chemical Education, Inc and ACS Publications Division of the American Chemical Society. 1155 Sixteenth Street NW, Washington, DC 20036. Tel: 800-227-5558; Tel: 202-872-4600; e-mail: eic@jce.acs.org; Web site: http://pubs.acs.org/jchemeduc
Publication Type: Journal Articles; Reports - Research
Education Level: Higher Education
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A